AAL open source system for the monitoring and intelligent control of nursing homes

[EN] SAFE-ECH is an innovative intelligent AAL open source system for monitoring nursing homes, that creates an Ambient Intelligent environment in a residence by collecting and storing sensor monitoring data, performing intelligent data analysis and specific actions to enhance the safety, comfort and efficient care of aged people. Our system implements open standards of the Open Geospatial Consortium complying with Observations & Measurements Schema (O&M), SensorML and Sensor Web Enablement (SWE) specifications. Our system adapts to the specific needs of each nursing home, integrating the required sensors, actuators, rules and services. It is scalable and allows the management of several residences simultaneously.This research was partially funded by the European Union's Horizon 2020 research and innovation programme as part of the INTERIoT project under Grant Agreement 687283, and by SAFE-ECH funded by the Spanish Ministerio de Industria, Economía y Competitividad (MINECO) under Grant Agreement RTC-2015-4502-1González-Usach, R.; Collado, V.; Esteve Domingo, M.; Palau Salvador, CE. (2017). AAL open source system for the monitoring and intelligent control of nursing homes. IEEE Systems, Man, and Cybernetics Society. 1-6. https://doi.org/10.1109/ICNSC.2017.8000072S1

Evolution of the body mass, height and BMI in participants of the Ultra-trail CSP- 115

Introducción: este estudio analiza, en 32 participantes que finalizaron el Ultratrail - CSP - 115, los cambios antropométricos sufridos en cuanto a masa corporal, altura e índice de masa corporal (IMC). Los objetivos del estudio son: analizar las diferencias entre salida y meta de mas a corporal, altura e IMC; y describir la evolución del peso durante el evento. Metodología: la masa corporal , altura e IMC fueron comparadas utilizando una prueba t de Student. Para describir la evolución de la masa corporal durante la carrera se utilizó un análisis de varianza (ANOVA) de medidas repetidas. Resultados: l os resultados obtenidos indican cambios es tadísticamente significativos para el análisis de ambos objetivos. Discusión y conclusiones : los resultados obtenidos son coherentes con otros estudios similares, aunque existen concreciones y matices interesantes. Destaca la pérdida de masa corporal de los c orredores, lo cual hace recomendable realizar medidas durante la carrera para evitar consecuencias negativas en la salud .Introduction: this study analyses anthropometric changes in terms of body mass, height and body mass index (BMI), in 32 finishers of the Ultratrail - CSP - 115 . The aims of the study are: to analyse the differences of body mass, height and BMI between the start and the finish of the race; and to describe the evolution of the weight during the event. Methodology: the body mass, height and BMI were compared using a T - S tudent test. To describe the evolution of body mass during the race an analysis of variance (ANOVA) for repeated measures was used. Results: s ignificant changes w ere observed in the analysis of both objectives. Discussion and conclusions: the results are consistent with other similar studies, although there are concretions and interesting nuances. It stresses the loss of body mass of runners, which makes it advisa ble to make measurements during the race to avoid negative health consequences.Este estudio se ha podido llevar a cabo gracias a la colaboración de Hospitales NISA, la Asociación de D iabetes de Castellón (ADI - CAS), Oximesa S.L.y Villarreal Club de Fútbol, S. A. D

Performance analysis of a ultra-compact low-power rectenna in paper substrate for RF energy harvesting

In this paper the experimental results of a compact low-power rectenna in paper substrate, designed to operate in the Wi-Fi band, are presented. The complete prototype, based on an annular slot antenna and a single-diode rectifier, features a weight of 1.5 grams and shows an RF-to-dc conversion efficiency in the design band of about 40 % for a -10 dBm available input power, of about 28 % at -15 dBm, and in the range [10, 22] % at -20 dBm, corresponding to an output DC voltage in the order of 320, 240 and 60 mV respectively. Additionally, the rectenna features an efficiency higher then 7 % in the whole band 1.8-2.7 dBm for a power density estimated around 3 μW/cm2.Grant numbers : The work was supported by the EU COST Action IC1301 WiPE (Wireless Power Transmission for sustainable Electronics). © 2017 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works

Possible chromosomal and germline integration of human herpesvirus 7

Publisher Copyright: © 2017 The Authors. Copyright: Copyright 2017 Elsevier B.V., All rights reserved.Human herpesvirus 7 (HHV-7) is a betaherpesvirus, and is phylogenetically related to both HHV-6A and HHV-6B. The presence of telomeric repeat sequences at both ends of its genome should make it equally likely to integrate into the human telomere as HHV-6. However, numerous studies have failed to detect germline integration of HHV-7, suggesting an important difference between the HHV-6A/-6B and HHV-7 genomes. In search of possible germline integrated HHV-7, we developed a sensitive and quantitative real-time PCR assay and discovered that primers designed against some parts of the HHV-7 genome can frequently miss HHV-7 positive clinical samples even though they work efficiently in cell-culture-derived HHV-7 positive materials. Using a primer pair against the U90 ORF of HHV-7, we identified a possible case of germline integration of HHV-7 with one copy of viral genome per cell in both peripheral blood cells and hair follicles. Chromosomal integration of HHV-7 in these individuals was confirmed by fluorescence in situ hybridization analysis. Germline integration of HHV-7 was further confirmed by detection of ~2.6 copies of HHV-7 in the hair follicles of one of the parents. Our results shed light on the complex nature of the HHV-7 genome in human-derived materials in comparison to cell-culture-derived materials and show the need for stringent criteria in the selection of primers for epidemiological HHV-7 studies.Peer reviewe

Simultaneous Surface Plasmon Resonance and X-ray Absorption Spectroscopy

We present here an experimental set-up to perform simultaneously measurements of surface plasmon resonance (SPR) and X-ray absorption spectroscopy (XAS) in a synchrotron beamline. The system allows measuring in situ and in real time the effect of X-ray irradiation on the SPR curves to explore the interaction of X-rays with matter. It is also possible to record XAS spectra while exciting SPR in order to detect the changes in the electronic configuration of thin films induced by the excitation of surface plasmons. Combined experiments recording simultaneously SPR and XAS curves while scanning different parameters can be carried out. The relative variations in the SPR and XAS spectra that can be detected with this set-up ranges from 10-3 to 10-5, depending on the particular experiment

OMERACT Definitions for Ultrasonographic Pathology and Elementary Lesions Of Rheumatic Disorders Fifteen Years On

Objective. The Outcome Measures in Rheumatology (OMERACT) ultrasound (US) working group (WG) operates research activities for the validation of US as an outcome measurement instrument according to the Filter 2.0 framework Methods. From the onset of the WG research in 2005 through now, original publications on definitions and scoring systems for pathophysiological manifestations and elementary lesions of various rheumatic disorders were reviewed Results. Definitions and scoring systems according to new terminology are provided Conclusions. We have redefined OMERACT definitions of US pathology and elementary lesions as well as scoring systems which are now proposed for OMERACT approval for application in clinical trial

Nonlinear software sensor for monitoring genetic regulation processes with noise and modeling errors

Nonlinear control techniques by means of a software sensor that are commonly used in chemical engineering could be also applied to genetic regulation processes. We provide here a realistic formulation of this procedure by introducing an additive white Gaussian noise, which is usually found in experimental data. Besides, we include model errors, meaning that we assume we do not know the nonlinear regulation function of the process. In order to illustrate this procedure, we employ the Goodwin dynamics of the concentrations [B.C. Goodwin, Temporal Oscillations in Cells, (Academic Press, New York, 1963)] in the simple form recently applied to single gene systems and some operon cases [H. De Jong, J. Comp. Biol. 9, 67 (2002)], which involves the dynamics of the mRNA, given protein, and metabolite concentrations. Further, we present results for a three gene case in co-regulated sets of transcription units as they occur in prokaryotes. However, instead of considering their full dynamics, we use only the data of the metabolites and a designed software sensor. We also show, more generally, that it is possible to rebuild the complete set of nonmeasured concentrations despite the uncertainties in the regulation function or, even more, in the case of not knowing the mRNA dynamics. In addition, the rebuilding of concentrations is not affected by the perturbation due to the additive white Gaussian noise and also we managed to filter the noisy output of the biological systemComment: 21 pages, 7 figures; also selected in vjbio of August 2005; this version corrects a misorder in the last three references of the published versio

Urolithin metabotypes can determine the modulation of gut microbiota in healthy individuals by tracking walnuts consumption over three days

Walnuts are rich in polyphenols ellagitannins, modulate gut microbiota (GM), and exert health benefits after long-term consumption. The metabolism of ellagitannins to urolithins via GM depends on urolithin metabotypes (UM-A, -B, or -0), which have been reported to predict host responsiveness to a polyphenol-rich intervention. This study aims to assess whether UMs were associated with differential GM modulation after short-term walnut consumption. In this study, 27 healthy individuals consumed 33 g of peeled raw walnuts over three days. GM profiling was determined using 16S rRNA illumina sequencing and specific real-time quantitative polymerase chain reactions (qPCRs), as well as microbial activity using short-chain fatty acids analysis in stool samples. UMs stratification of volunteers was assessed using ultra performance liquid chromatography-electro spray ionization-quadrupole time of flight-mass spectrometry (UPLC-ESI-QTOF-MS) analysis of urolithins in urine samples. The gut microbiota associated with UM-B was more sensitive to the walnut intervention. Blautia, Bifidobacterium, and members of the Coriobacteriaceae family, including Gordonibacter, increased exclusively in UM-B subjects, while some members of the Lachnospiraceae family decreased in UM-A individuals. Coprococcus and Collinsella increased in both UMs and higher acetate and propionate production resulted after walnuts intake. Our results show that walnuts consumption after only three days modulates GM in a urolithin metabotype-depending manner and increases the production of short-chain fatty acids (SCFA)

Effect of Impurity Scattering on the Nonlinear Microwave Response in High-Tc Superconductors

We theoretically investigate intermodulation distortion in high-Tc superconductors. We study the effect of nonmagnetic impurities on the real and imaginary parts of nonlinear conductivity. The nonlinear conductivity is proportional to the inverse of temperature owing to the dependence of the damping effect on energy, which arises from the phase shift deviating from the unitary limit. It is shown that the final-states interaction makes the real part predominant over the imaginary part. These effects have not been included in previous theories based on the two-fluid model, enabling a consistent explanation for the experiments with the rf and dc fields

Diferenciación y desarrollo postnatal de los tipos de fibras musculares en el cerdo chato murciano

Mediante la técnica que detecta la actividad de la enzima ATPasa miosínica se analiza el tamaño y porcentajes de los distintos tipos de fibras que integran el músculo longísimo lumbar del cerdo “Chato Murciano”, desde el nacimiento hasta los 120 días de edad. Al nacimiento, el músculo longísimo está conformado por un 5,5% de fibras tipo I, de gran tamaño y un 94,5% de fibras tipo II, de menor tamaño. Durante el primer mes de vida postnatal las fibras tipo II se irán diferenciando en nuevas fibras tipo I y subtipos IIA y IIX. A partir de los dos meses tiene lugar un aumento del diámetro fibrilar (hipertrofia) y una distribución fibrilar que recuerda a la de animales adultos. Aunque la hipertrofia observada afecta a los tres tipos de fibras evaluados, parece claro que el crecimiento y conformación muscular en el cerdo chato murciano está muy asociado al notable incremento en diámetro que experimentan las fibras IIX, ya que éstas crecen más rápidamente que las tipo I y IIA